Abstract
Myelin oligodendrocyte glycoprotein (MOG) antibody disease is an autoimmune disease
of the central nervous system associated with a serological antibody against MOG,
a glycoprotein expressed on the outer membrane of myelin. It is solely found within
the central nervous system in the brain, optic nerves and spinal cord. MOG antibody
disease falls within the neuromyelitis optica spectrum disorders (NMOSD), however
clinical characteristics appear distinct from aquaporin-4 antibody related disease
and multiple sclerosis. It has predilection for causing recurrent optic neuritis and
transverse myelitis. Accurate diagnosis is important to determine long term prognosis
and suitable treatment. We describe the case of a 42 year old woman previously labelled
as MS who demonstrated a variable presentation of MOG antibody disease.
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Article info
Publication history
Published online: June 26, 2020
Accepted:
June 25,
2020
Received in revised form:
June 25,
2020
Received:
May 27,
2020
Identification
Copyright
© 2020 Elsevier B.V. All rights reserved.
