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Editors Welcome| Volume 38, 101953, February 2020

Ageing and multiple sclerosis

Published:February 01, 2020DOI:https://doi.org/10.1016/j.msard.2020.101953
      Is premature ageing a driver of late worsening in people with multiple sclerosis?
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      References

        • Bartels M.N.
        • Omura A.
        Aging in polio.
        Phys. Med. Rehabil. Clin. N. Am. 2005; 16: 197-218
        • Di Francesco A.
        • Di Germanio C.
        • Bernier M.
        • de Cabo R.
        A time to fast.
        Science. 2018; 362: 770-775
        • Fontana L.
        • Nehme J.
        • Demaria M.
        Caloric restriction and cellular senescence.
        Mech. Ageing. Dev. 2018; 176: 19-23
        • Giovannoni G.
        • Butzkueven H.
        • Dhib-Jalbut S.
        • Hobart J.
        • Kobelt G.
        • Pepper G.
        • et al.
        Brain health: time matters in multiple sclerosis.
        Mult. Scler. Relat. Disord. 2016; 9: S5-48
        • Guan J.-.Z.
        • Guan W.-.P.
        • Maeda T.
        • Guoqing X.
        • GuangZhi W.
        • Makino N.
        Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening.
        Mol. Cell. Biochem. 2015; 400: 183-187
        • Krysko K.M.
        • Henry R.G.
        • Cree B.A.C.
        • Lin J.
        • Caillier S.
        • University of California, San Francisco MS-EPIC Team
        Telomere length is associated with disability progression in multiple sclerosis.
        Ann. Neurol. 2019; 86: 671-682
        • Moreno C.L.
        • Mobbs C.V.
        Epigenetic mechanisms underlying lifespan and age-related effects of dietary restriction and the ketogenic diet.
        Mol. Cell. Endocrinol. 2017; 455: 33-40
        • Nicaise A.M.
        • Wagstaff L.J.
        • Willis C.M.
        • Paisie C.
        • Chandok H.
        • Robson P.
        • et al.
        Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis.
        Proc. Natl. Acad. Sci. USA. 2019; 116: 9030-9039
        • Opfer R.
        • Ostwaldt A.-C.
        • Sormani M.P.
        • Gocke C.
        • Walker-Egger C.
        • Manogaran P.
        • et al.
        Estimates of age-dependent cutoffs for pathological brain volume loss using SIENA/FSL – a longitudinal brain volumetry study in healthy adults.
        Neurobiol. Aging. 2018; 65: 1-6
        • Pettigrew C.
        • Soldan A.
        Defining cognitive reserve and implications for cognitive aging.
        Curr. Neurol. Neurosci. Rep. 2019; 19: 1
        • Rosenthal J.
        • Tyor W.
        Aging, comorbidities, and the importance of finding biomarkers for HIV-associated neurocognitive disorders.
        J. Neurovirol. 2019; 25: 673-685
        • Sumowski J.F.
        • Rocca M.A.
        • Leavitt V.M.
        • Meani A.
        • Mesaros S.
        • Drulovic J.
        • et al.
        Brain reserve against physical disability progression over 5 years in multiple sclerosis.
        Neurology. 2016; 86: 2006-2009