Advertisement

Obesity, dieting, and multiple sclerosis

Published:December 09, 2019DOI:https://doi.org/10.1016/j.msard.2019.101889

      Highlights

      • Thirty-seven percent of participants were obese.
      • People with multiple sclerosis were no more likely to adopt a diet than controls.
      • Being obese, younger, female, or non-Hispanic were associated with dieting.

      Abstract

      Background

      Obesity is common in the United States and is associated with a higher risk of relapse and comorbidities, and increased disease progression, in people with MS.

      Methods

      We examined the prevalence of overweight and obesity in the MS Sunshine Study, a matched case-control study of multiple sclerosis in Southern California (470 cases, 519 controls). We reported the proportion of participants who adopted a specific diet for nutrition or weight loss purposes, and identified independent predictors of dieting.

      Results

      In the total population, 32% and 37% were overweight and obese, respectively. Case participants were no more likely to adopt a specific diet for nutrition or weight loss purposes than control participants (10% and 11%, respectively). Being obese, younger, female or non-Hispanic were independently associated with dieting.

      Conclusion

      Despite the evidence that obesity can worsen MS prognosis, and the high prevalence of overweight/obesity, case participants were no more likely to adopt a specific diet than control participants. Improved nutrition education may help people with MS make healthy dietary changes for nutrition or weight loss purposes.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Multiple Sclerosis and Related Disorders
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Brenton J.N.
        • Goldman M.D.
        A study of dietary modification: perceptions and attitudes of patients with multiple sclerosis.
        Mult. Scler. Relat. Disord. 2016; 8: 54-57https://doi.org/10.1016/j.msard.2016.04.009
        • Fitzgerald K.C.
        • Tyry T.
        • Salter A.
        • Cofield S.S.
        • Cutter G.
        • Fox R.J.
        • Marrie R.A.
        A survey of dietary characteristics in a large population of people with multiple sclerosis.
        Mult. Scler. Relat. Disord. 2018; 22: 12-18https://doi.org/10.1016/j.msard.2018.02.019
        • Hales C.M.
        • Carroll M.D.
        • Fryar C.D.
        • Ogden C.L.
        Prevalence of Obesity among Adults and Youth: United States.
        National Center for Health Statistics, Hyattsville, MD2017: 2015-2016 (National Center for Health Statistics data brief, no. 288Retrieved from)
        • Langer-Gould A.
        • Lucas R.
        • Xiang A.
        • Chen L.
        • Wu J.
        • Gonzalez E.
        • Barcellos L.
        MS sunshine study: Sun exposure but not vitamin d is associated with multiple sclerosis risk in blacks and hispanics.
        Nutrients. 2018; 10: 268https://doi.org/10.3390/nu10030268
        • Marrie R.A.
        Comorbidity in multiple sclerosis: implications for patient care.
        Nat. Rev. Neurol. 2017; 13https://doi.org/10.1038/nrneurol.2017.33
        • Martin C.B.
        • Herrick K.A.
        • Sarafrazi N.
        • Ogden C.L.
        Attempts to Lose Weight among Adults in the United States.
        National Center for Health Statistics. Retrieved from, Hyattsville, MD2018: 2013-2016 (NCHS Data Brief, no. 313)
        • Riemann-Lorenz K.
        • Eilers M.
        • von Geldern G.
        • Schulz K.-H.
        • Köpke S.
        • Heesen C.
        Dietary interventions in multiple sclerosis: development and pilot-testing of an evidence based patient education program.
        PLoS ONE. 2016; 11e0165246https://doi.org/10.1371/journal.pone.0165246
        • Russell R.D.
        • Lucas R.M.
        • Brennan V.
        • Sherriff J.L.
        • Begley A.
        • Black L.J.
        • The Ausimmune Investigator Group
        • The Ausimmune Investigator Group
        Reported changes in dietary behavior following a first clinical diagnosis of central nervous system demyelination.
        Front. Neurol. 2018; 9: 1-7https://doi.org/10.3389/fneur.2018.00161
        • Stampanoni Bassi M.
        • Iezzi E.
        • Buttari F.
        • Gilio L.
        • Simonelli I.
        • Carbone F.
        • Matarese G.
        Obesity worsens central inflammation and disability in multiple sclerosis.
        Multiple Sclerosis Journal. 2019; ([Epub ahead of print])https://doi.org/10.1177/1352458519853473
        • Tettey P.
        • Simpson S.
        • Taylor B.
        • Ponsonby A.-.L.
        • Lucas R.M.
        • Dwyer T.
        • van Der Mei I.A.
        An adverse lipid profile and increased levels of adiposity significantly predict clinical course after a first demyelinating event.
        Journal of Neurology, Neurosurgery & Psychiatry. 2017; 88: 395-401https://doi.org/10.1136/jnnp-2016-315037