Multiple sclerosis (MS) is an inflammatory disease of central nervous system and its prevalence is increasing globally. It is known that both genetics and environmental factors play a role as risk factors of the disease. Many studies have been done before to clarify those risk factors in Caucasian population but unfortunately there isn't any comprehensive and systematic study in Middle East & North Africa (MENA) region. Therefore we aimed to gather those environmental risk factors mentioned in MENA region by a systematic review method.
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