Highlights
- •Pneumonitis can occur following treatment with the monoclonal antibody alemtuzumab in a patient with multiple sclerosis.
- •In a patient presenting with breathlessness post alemtuzumab infusion a non-infectious cause needs to be considered.
- •Pneumonitis secondary to alemtuzumab can potentially be managed with oral steroids alone.
Abstract
The most common adverse events associated with the monoclonal antibody alemtuzumab
are infusion associated reactions and secondary autoimmune disease. Respiratory complications
are unusual following treatment with alemtuzumab, but can be precipitated by an infectious
cause. We describe a case of a sub-acute steroid responsive non-infectious pneumonitis
affecting a 51 year old woman, who presented one month after initiation of therapy
for multiple sclerosis with alemtuzumab.
Keywords
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Article info
Publication history
Published online: April 03, 2018
Accepted:
April 2,
2018
Received in revised form:
March 5,
2018
Received:
January 17,
2018
Identification
Copyright
© 2018 Elsevier B.V. All rights reserved.
