- •A systematic review of the epidemiology of PPMS in LATAM was performed.
- •No incidence data were found regarding PPMS.
- •Differentiated prevalence was reported in 7 studies and ranged from 0.13 to 1.1 cases of PPMS per 100,000 inhabitants.
- •Regarding subtype frequency, PPMS was observed in 10% of affected patients in proportional meta-analysis.
- •The study provides information on discriminated epidemiological features of PPMS in the region.
Novel epidemiological data has appeared in recent years in Latin America (LATAM) regarding the epidemiology of multiple sclerosis (MS); however, most of this information is related to all MS subtypes, and no specific data was collected regarding the primary progressive form of MS (PPMS). The objective of this study was to perform an updated systematic review of the epidemiology of PPMS in LATAM.
We conducted a systematic review of published epidemiological articles of PPMS from January 1997 to June 2017.
No incidence data were found regarding PPMS. Differentiated prevalence was reported in 7 studies and ranged from 0.13 to 1.1 cases of PPMS per 100,000 inhabitants. Regarding subtype frequency, PPMS was observed in 10% of affected patients in proportional meta-analysis. No data about mortality were found.
The study provides information on discriminated epidemiological features of PPMS in the region. The frequency observed was low in terms of prevalence. Follow up studies considering survival milestones and incidence data could provide a better understanding of the disease in the region.
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Published online: February 23, 2018
Accepted: February 22, 2018
Received in revised form: February 20, 2018
Received: November 24, 2017
© 2018 Elsevier B.V. All rights reserved.