Highlights
- •A systematic review of the epidemiology of PPMS in LATAM was performed.
- •No incidence data were found regarding PPMS.
- •Differentiated prevalence was reported in 7 studies and ranged from 0.13 to 1.1 cases of PPMS per 100,000 inhabitants.
- •Regarding subtype frequency, PPMS was observed in 10% of affected patients in proportional meta-analysis.
- •The study provides information on discriminated epidemiological features of PPMS in the region.
Abstract
Novel epidemiological data has appeared in recent years in Latin America (LATAM) regarding
the epidemiology of multiple sclerosis (MS); however, most of this information is
related to all MS subtypes, and no specific data was collected regarding the primary
progressive form of MS (PPMS). The objective of this study was to perform an updated
systematic review of the epidemiology of PPMS in LATAM.
Methods
We conducted a systematic review of published epidemiological articles of PPMS from
January 1997 to June 2017.
Results
No incidence data were found regarding PPMS. Differentiated prevalence was reported
in 7 studies and ranged from 0.13 to 1.1 cases of PPMS per 100,000 inhabitants. Regarding
subtype frequency, PPMS was observed in 10% of affected patients in proportional meta-analysis.
No data about mortality were found.
Conclusion
The study provides information on discriminated epidemiological features of PPMS in
the region. The frequency observed was low in terms of prevalence. Follow up studies
considering survival milestones and incidence data could provide a better understanding
of the disease in the region.
Keywords
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Article info
Publication history
Published online: February 23, 2018
Accepted:
February 22,
2018
Received in revised form:
February 20,
2018
Received:
November 24,
2017
Identification
Copyright
© 2018 Elsevier B.V. All rights reserved.
