Highlights
- •In Poland, the number of patients with MS was previously unknown.
- •This work presents the results and is an attempt to identify MS prevalence in Poland.
- •This is the first data that obtained the level of MS prevalence in Poland. The data confirm that Poland is a high-risk area for MS.
Abstract
Objective
The prevalence of multiple sclerosis (MS)was previously unknown in Poland. The aim
of this study was to determine the prevalence of MS in Poland.
Methods
MS prevalence was determined on the basis of data from the Swietokrzyskie (central
Poland) and Podlaskie (northeastern Poland) Voivodeships. The area population on the
prevalence study day (December 31, 2013) was 1,268,239 (649,007 women; 619,232 men)
in central and 1,195,625 (612,979 women; 582,646 men) in northeastern Poland.
Results
The overall crude prevalence rate of confirmed MS patients was 109.1/100,000 (95%
confidence interval[CI]103.5–115.0) in the Swietokrzyskie and 108.7/100,000 (95% CI
103.0–114.7) in the Podlaskie Voivodeships. A significantly higher prevalence was
recorded in females (149.8/100,000, 95% CI 140.6–159.3 vs. 142.4/100,000, 95% CI 133.3–152.0)
than in males (66.5/100,000, 95% CI 60.4–73.1 vs.57.8/100,000, 95% CI 52.0–64.2)(p < 0.001).
Age-adjusted rates for the Polish Standard Population were the same in both regions
(110.3/100,000 (95% CI 104.6–116.1) vs.110.9/100,000 (95% CI 105.1–117.1)) and for
the European Standard Population did not different statistically between both voivodeships
(103.9/100,000 (95% CI 98.6–109.5) vs.108.5/100,000 (95% CI 102.7–114.5)).
Conclusion
This is the first data that obtained the level of MS prevalence in Poland and confirmed
that Poland is a high-risk area for multiple sclerosis.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Multiple Sclerosis and Related DisordersAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- High nationwide prevalence of multiple sclerosis in Sweden.Mult. Scler. 2011; 17: 901-908
Area and population in the territorial profile in 2013, 2013. Polish Central Statistical Office.
Atlas of MS 2013, 2013. Multiple Sclerosis International Federation, London.
- Prevalence of multiple sclerosis in Denmark 1950-−2005.Mult. Scler. 2010; 16: 520-525
- High prevalence of multiple sclerosis in the Swedish county of Varmland.Mult. Scler. 2009; 15: 1253-1262
- Prevalence and incidence of multiple sclerosis in central Poland, 2010–2014.BMC Neurol. 2016; 16: 134
- Multiple sclerosis in a small urban community in central Poland.J. Neurol. Sci. 1965; 2: 82-86
- Epidemiological Study of multiple sclerosis in western Poland.Eur. Neurol. 1969; 2: 90-108
- Confidence intervals for directly standardize rates: a method based on the gamma distribution.Stat. Med. 1997; 16: 791-801
- Multiple sclerosis registry in Germany: results of the extension phase 2005/2006.Dtsch Arztebl Int. 2008; 105: 113-119
- Występowanie stwardnienia rozsianego wśród mieszkańców miasta Tczew położonego na północy Polski.Neurol. Neurochir. Pol. 1996; 30: 77
- A 60-year follow-up of the incidence and prevalence of multiple sclerosis in Hordaland County, Western Norway.J. Neurol. Neurosurg. Psychiatry. 2016; 87: 100-105
- Epidemiological Data on Multiple Sclerosis From an Industrial Area in North-west Germany. Multiple Sclerosis in Europe: An Epidemiological Update.Leuchtturm-Verlag/LTV Press, Darmstadt1994: 143-146
- Multiple sclerosis epidemiology in Middle East and North Africa: a systematic review and meta-analysis.Neuroepidemiology. 2015; 44: 232-244
- Multiple sclerosis relapses: epidemiology, outcomes and management. A systematic review.Neuroepidemiology. 2015; 44: 199-214
- Association of influenza incidence with multiple sclerosis onset.Folia Neuropathol. 2004; 42: 19-24
- Selected aspects of the epidemiology of multiple sclerosis in Poland – a multicentre pilot study.Neurol. Neurochir. Pol. 2010; 44: 443-452
- Epidemiology in multiple sclerosis: a pilgrim's progress.Brain. 2013; 136: 2904-2917
- On the epidemiology of multiple sclerosis in the Middle East and North Africa.Neuroepidemiology. 2015; 44: 245-248
- Socioeconomic trends in hospitalization for multiple sclerosis.Neuroepidemiology. 2010; 35: 93-99
- Epidemiological aspects of multiple sclerosis in Lublin (Poland).Neurol. Neurochir. Pol. 2004; 38: 361-366
- Demographic characteristics of MS patients in Poland's upper Silesia region.Int. J. Neurosci. 2015; 125: 344-351
- Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria.Ann. Neurol. 2011; 69: 292-302
- New diagnostic criteria for multiple sclerosis: guidelines for research protocols.Ann. Neurol. 1983; 13: 227-231
- The Epidemiology of Multiple Sclerosis in Southern Lower Saxony. Multiple Sclerosis in Europe: An Epidemiological Update.Leuchtturm-Verlag/LTV Press, Darmstadt1994: 130-133
- Epidemiology of multiple sclerosis in the region of Szczecin: prevalence and incidence 1993–1995.Neurol. Neurochir. Pol. 1999; 33: 575-585
- An epidemiological survey of a focus of multiple sclerosis in the province of Szczecin.Przeg. Epidemiol. 2001; 55: 331-341
- Multiple sclerosis in Poland and worldwide- epidemiological considerations.Aktual. Neurol. 2009; 9: 91-97
Potemkowski A., Jasińska E., 2015. Epidemiological characteristics of multiple sclerosis in the town of Kielce (central Poland)-ten years of prospective observation (2003–2012). Poster presentation at ECTRIMS Meeting, 8 October, Barcelona, Spain.
- Problems of experimental trials of therapy in multiple sclerosis: report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis.Ann. N.Y. Acad. Sci. 1965; 122: 552-568
Size and structure of population, 2014. Demographic Yearbook of Poland 2014. Warsaw: Central Statistical Office, p.84.
- Incidence of MS during two fifteen- year periods in the Gothenburg region of Sweden.Acta Neurol. Scand. 1990; 82: 161-168
- Epidemie roztroušené sklerózy ve světě?.Cesk Slov. Neurol. N. 2012; 75/108: 701-706
- Epidemiology of multiple sclerosis in Western Poland – a comparison between prevalence rates in 1965 and 1981.Acta Neurol. Scand. 1985; 72: 210-217
- Multiple sclerosis: its prevalence and incidence in the population of western Poland.Neurol. Neurochir. Pol. 1987; 1: 33-39
Article info
Publication history
Published online: February 12, 2018
Accepted:
February 10,
2018
Received in revised form:
January 25,
2018
Received:
September 6,
2017
Identification
Copyright
© 2018 Elsevier B.V. All rights reserved.
