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Editorial| Volume 21, PA3-A5, April 2018

Can falling infection rates in one country explain rising incidence of autoimmune and allergic diseases in other countries? Caution when (over) interpreting ecological data from disparate areas

  • Helen Tremlett
    Correspondence
    Correspondence to: Faculty of Medicine, Division of Neurology, University of British Columbia, Room S126, 2211 Wesbrook Mall, Vancouver, BC, Canada V6T 2B5.
    Affiliations
    Division of Neurology, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada

    Centre for Brain Health and Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, Canada
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  • Rachael Rodney
    Affiliations
    National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, Canberra, Australia
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  • Robyn Lucas
    Affiliations
    National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, Canberra, Australia

    Centre for Ophthalmology and Visual Sciences, University of Western Australia, Perth, Western Australia, Australia
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Published:November 03, 2017DOI:https://doi.org/10.1016/j.msard.2017.11.001
      Myths are common in science.
      • Scudellari M.
      The science myths that will not die.
      Once assimilated into popular belief or medicine, they can be difficult to dispel, with consequences that may not be trivial. They have the potential to hold back some avenues of science, (
      • Scudellari M.
      The science myths that will not die.
      ) inhibit publication of studies that refute ‘what is already known,’ and misdirect research or healthcare dollars.

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      References

        • Bach J.F.
        The effect of infections on susceptibility to autoimmune and allergic diseases.
        N. Engl. J. Med. 2002; 347: 911-920
        • Dubois P.
        • Degrave E.
        • Vandenplas O.
        Asthma and airway hyperresponsiveness among Belgian conscripts, 1978-91.
        Thorax. 1998; 53: 101-105
        • Farrokhyar F.
        • Swarbrick E.T.
        • Irvine E.J.
        A critical review of epidemiological studies in inflammatory bowel disease.
        Scand. J. Gastroenterol. 2001; 36: 2-15
        • Gale E.A.
        The rise of childhood type 1 diabetes in the 20th century.
        Diabetes. 2002; 51: 3353-3361
        • Huttenhower C.
        Structure and function of the human microbiome.
        in: Institute B. LabRoots. Harvard University, 2015
        • Joussemet M.
        • Depaquit J.
        • Nicand E.
        • et al.
        [Fall in the seroprevalence of hepatitis A in French youth].
        Gastroenterol. Clin. Biol. 1999; 23 (447-5)
        • Kingwell E.
        • Zhu F.
        • Marrie R.A.
        • et al.
        High incidence and increasing prevalence of multiple sclerosis in British Columbia, Canada: findings from over two decades (1991–2010).
        J. Neurol. 2015; 262: 2352-2363
      1. Knight R., 2016. Breaking the Wall to Our Microbial Self. Falling Walls Conference Berlin, Germany. 〈https://www.youtube.com/watch?V=R-QaEnO1bcY〉.

        • Krolewski A.
        • Warram J.
        • Rand L.
        • Kahn R.
        Epidemiologic approach to the etiology of type 1 diabetes mellitus and its complications.
        N. Engl. J. Med. 1987; 317: 1390-1398
        • Mackenzie I.S.
        • Morant S.V.
        • Bloomfield G.A.
        • MacDonald T.M.
        • O'Riordan J.
        Incidence and prevalence of multiple sclerosis in the UK 1990–2010: a descriptive study in the General Practice Research Database.
        J. Neurol. Neurosurg. Psychiatry. 2014; 85: 76-84
        • Marrie R.A.
        • Yu N.
        • Blanchard J.
        • Leung S.
        • Elliott L.
        The rising prevalence and changing age distribution of multiple sclerosis in Manitoba.
        Neurology. 2010; 74: 465-471
        • Marrie R.A.
        • Fisk J.D.
        • Stadnyk K.J.
        • et al.
        The incidence and prevalence of multiple sclerosis in Nova Scotia, Canada.
        Can. J. Neurol. Sci. 2013; 40: 824-831
        • Pugliatti M.
        • Sotgiu S.
        • Solinas G.
        • et al.
        Multiple sclerosis epidemiology in Sardinia: evidence for a true increasing risk.
        Acta Neurol. Scand. 2001; 103: 20-26
        • Ribbons K.
        • Lea R.
        • Tiedeman C.
        • Mackenzie L.
        • Lechner-Scott J.
        Ongoing increase in incidence and prevalence of multiple sclerosis in Newcastle, Australia: a 50-year study.
        Mult. Scler. 2016; (1352458516671819)
        • Scudellari M.
        The science myths that will not die.
        Nature. 2015; 528: 322-325
        • Strachan D.P.
        Hay fever, hygiene, and household size.
        BMJ. 1989; 299: 1259-1260
        • Tuomilehto J.
        • Karvonen M.
        • Pitkaniemi J.
        • et al.
        Record-high incidence of Type I (insulin-dependent) diabetes mellitus in Finnish children.
        Finn. Child. Type I Diabetes Regist. Group. Diabetol. 1999; 42: 655-660
        • World Bank
        Incidence of Tuberculosis. 2017; (Accessed 14 June 2017)