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Review article| Volume 14, P56-59, May 2017

Infectious mononucleosis and multiple sclerosis – Updated review on associated risk

Published:March 27, 2017DOI:https://doi.org/10.1016/j.msard.2017.02.019
Infectious mononucleosis and multiple sclerosis – Updated review on associated risk
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      Abstract

      Background

      There has been substantial evidence accumulating on the role of infectious mononucleosis (IM) and the subsequent risk of obtaining Multiple Sclerosis (MS). Up to date studies not previously explored were reviewed by the author to further clarify the association.

      Methods

      Medline and Web of Science were searched with no time constraints for articles exploring an association between Multiple Sclerosis and Infectious Mononucleosis. 24 articles were found, totalling 1063 cases and 13,227 cohort/controls.

      Results

      23/24 (96%) articles reported a significant association of Infectious Mononucleosis on the risk of subsequent multiple sclerosis.

      Discussion

      Overall, new literature on IM and risk of MS categorically supports the association. Future work should focus on other risk factors such as age and gender on IM and subsequent risk of MS.

      Keywords

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      Article info

      Publication history

      Published online: March 27, 2017
      Accepted: February 25, 2017
      Received in revised form: February 20, 2017
      Received: December 27, 2016

      Identification

      DOI: https://doi.org/10.1016/j.msard.2017.02.019

      Copyright

      Crown Copyright © 2017 Published by Elsevier B.V. All rights reserved.

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