Highlights
- •Unique clinical presentation with a painful erythema in neuromyelitis optica.
- •First case of neuromyelitis optica onset with an area postream syndrome triggered by a yellow fever vaccination.
- •Correlation of the area postrema syndrome and painful erythema with MRI-images.
- •Photo image of the painful erythema for illustration.
Abstract
Neuromyelitis Optica Spectrum Disorder (NMOSD) is an immune-mediated disease of the
central nervous system with the presence of aquaporin 4-antibodies (AQP4-abs) in most
cases. We describe a patient who developed NMOSD after a yellow fever vaccination.
He presented to us with an unusual painful erythema Th7-9 triggered by touch in the
respective skin area due to a cervical spinal cord lesion affecting the dorsolateral
parts of C6/7. To our knowledge, this is the first case of NMOSD with such a clinical
presentation expanding the clinical spectrum of NMOSD. It is important to be aware
of that a yellow fever vaccination can trigger NMOSD.
Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Multiple Sclerosis and Related DisordersAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Longitudinal myelitis associated with yellow fever vaccination.J. Neurovirol. 2009; 15: 348-350
- Vasodilatation in hyperalgesic rat skin evoked by stimulation of afferent A[beta]-fibers: further evidence for a role of dorsal root reflexes in allodynia.Pain. 2001; 94: 283-291
- A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis.Lancet. 2004; 364: 2106-2112
- Neuromyelitis optica following human papillomavirus vaccination.Neurology. 2012; 79: 285-287
- International consensus diagnostic criteria for neuromyelitis optica spectrum disorders.Neurology. 2015; 85: 177-189
Article info
Publication history
Published online: November 26, 2016
Accepted:
November 25,
2016
Received:
November 15,
2016
Identification
Copyright
© 2016 Elsevier B.V. All rights reserved.
