- •Brain volume declines after hematopoietic stem cell transplantation (HSCT) in MS.
- •Cognition declines in the initial period following HSCT.
- •The cognitive decline has little relationship to volume changes.
- •With temporal distance from HSCT, cognition returns to baseline levels.
- •Immunoablation and HSCT may have no lasting deleterious effects on cognition.
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Multiple Sclerosis and Related Disorders
- Association of neocortical volume changes with cognitive deterioration in relapsing-remitting multiple sclerosis.Archives of Neurology. 2007; 64: 1157-1161
- Neuropsychologic impairment in adult bone marrow transplant candidates.Cancer. 1992; 70 ([ref. type: abstract]): 2288-2297
Benedict RHB, Bakshi R, Simon JH, Priore R, Miller C, Munschauer F, Frontal cortex atrophy predicts cognitive impairment in multiple sclerosis, Journal of Neuropsychiatry and Clinical Neuroscience 14, 2002, 44-51.
Benedict RHB, Effects of usingsame- versus alternate-form memory tests during short-interval repeated assessments in multiple sclerosis, Journal of the International Neuropsychological Society 11, 2005, 727-736
Berard J, Walker LAS, Bharadia V, Bowman M, Lee H, Atkins HL, et al. Neuroimaging correlates of cognitive change following immunoablative therapy and bone marrow transplant in MS: a pilot study. In: Proceedings of the annual meeting of the International Neuropsychological Society conference; 2012.
- Characteristics and correlates of cognitive functioning following bone marrow transplantation.Bone Marrow Transplantation. 2005; 36 ([ref. type: abstract]): 695-702
- Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis.Neurology. 2006; 66: 1935-1937
- Cognitive effects of chemotherapy in post menopausal breast cancer patients 1 year after treatment.Psycho-Oncology. 2009; 18: 134-143
- The nature of memory impairments in multiple sclerosis: acquisition versus retrieval.Journal of Clinical and Experimental Neuropsychology. 1994; 16: 183-189
- Acquisition and storage deficits in multiple sclerosis.Journal of Clinical and Experimental Neuropsychology. 1998; 20: 376-390
- Is speed of processing or working memory the primary information processing deficit in multiple sclerosis?.Journal of Clinical and Experimental Neuropsychology. 2004; 26: 550-562
- Cognitive impairment in relapsing and primary progressive multiple sclerosis: mostly a matter of speed.Journal of the International Neuropsychological Society. 2004; 10: 948-956
- A 3-year longitudinal study of cognitive impairment in patients with primary progressive multiple sclerosis: speed matters.Journal of the Neurological Sciences. 2008; 267: 129-136
- Psychometrics and normative data for the multiple sclerosis functional composite: replacing the PASAT with the symbol digit modalities test.Multiple Sclerosis. 2010; 16: 228-237
- Bone marrow transplantation: does it stop MS progression?.Journal of the Neurological Sciences. 2007; 259: 85-89
- Course of cognitive decline in hematopoietic stem cell transplantation: a within-subjects design.Archives of Clinical Neuropsychology. 2009; 24 ([ref. type: abstract]): 689-698
- A comparison of memory performance in relapsing-remitting, primary progressive and secondary progressive, multiple sclerosis.Neuropsychiatry, Neuropsychology and Behavioral Neurology. 2001; 14: 32-44
- Cognitive functioning and quality of life in long-term adult survivors of bone marrow tranplantation.Cancer. 2002; 95 ([ref. type: abstract]): 183-192
- Cognitive impairment in multiple sclerosis.Current Opinion in Neurology. 2007; 20: 275-280
- Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation.Journal of Neurology, Neurosurgery and Psychiatry. 2004; 75: 643-644
- Changes in cognitive functioning in the year after hematopoietic stem cell transplantation.Cancer. 2007; 110 ([ref. type: abstract]): 1560-1567
- Evaluation of the neurobehavioral functioning of patients before, during, and after bone marrow transplantation.Journal of Clinical Oncology. 1994; 12 ([ref. type: abstract]): 820-826
- Hematopoietic stem cell transplantation for multiple sclerosis: collaboration of the CIBMTR and EBMT to facilitate international clinical studies.Biology of Blood and Marrow Transplantation. 2010; 16: 1076-1083
- Reaction time: an alternative method for assessing the effects of multiple sclerosis on information processing speed.Archives of Clinical Neuropsychology. 2007; 22: 655-664
- The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study.Multiple Sclerosis. 2007; 13: 1068-1070
Roosendaal SD, Bendfeldt K, Vrenken H, Polman CH, Borgwardt S, Radue EW et al., Grey matter volume in a large cohort of MS patients: relation to MRI parameters and disability, Multiple Sclerosis Journal 17, 2011, 1098-1106.
- Clinical and MRI outcome after autologous hematopoietic stem cell transplantation in MS.Neurology. 2004; 62: 282-284
Sanfilipo MP, Benedict, RHB, Weinstock-Guttman B., Bakshi R., Gray and white matter brain atrophy and neuropsychological impairment in multiple sclerosis, Neurology 66, 2006, 685-692.
- The effects of adjuvant chemotherapy on cognition in women with breast cancer—preliminary results of an observational longitudinal study.Breast. 2005; 14: 142-150
- Accurate, robust and automated longitudinal and cross-sectional brain change analysis.NeuroImage. 2002; 17: 479-489
Tombaugh TN, Berrigan LI, Walker LAS, Freedman MS. The Computerized Test of Information Processing (CTIP) offers an alternative to the PASAT for assessing cognitive processing speed in individuals with multiple; 2010.
- PASAT performance before and after immunoablative therapy and bone marrow transplant in individuals with MS.Journal of the International Neuropsychological Society. 2012; 18 ([ref. type: abstract]): 19