The cornerstone for a clinical diagnosis of multiple sclerosis (MS) is the demonstration
of dissemination in space (DIS) and time (DIT) of lesions in the central nervous system
suggestive of demyelination in the absence of a differential diagnosis that would
better explain a patient's symptoms (
Polman and Reingold, 2011
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References
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Article info
Publication history
Published online: March 04, 2013
Identification
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© 2013 Elsevier B.V. Published by Elsevier Inc. All rights reserved.