Commentary| Volume 2, ISSUE 3, P154-155, July 2013

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A single lesion—And yet MS?

      The cornerstone for a clinical diagnosis of multiple sclerosis (MS) is the demonstration of dissemination in space (DIS) and time (DIT) of lesions in the central nervous system suggestive of demyelination in the absence of a differential diagnosis that would better explain a patient's symptoms (
      • Polman C.H.
      • Reingold S.C.
      • et al.
      Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria.
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