Abstract
Inflammatory brain diseases in childhood are underrecognized and lead to life-threatening
neurological deficits. Early recognition and diagnosis of inflammatory brain diseases
is critical, as the reversibility of the neurological deficits is closely related
to early initiation of treatment and prevention of secondary brain tissue damage.
Primary childhood CNS vasculitis is the most common cause of inflammatory brain disease
in childhood. Clinical features, laboratory tests and imaging can be non-conclusive
and overlap with other inflammatory brain diseases, such as demyelinating diseases.
This review focuses on recent publications on epidemiology, pathogenesis, and treatment
in childhood CNS vasculitis and relevant publications from the rapidly expanding differential
diagnosis for the subtypes of CNS vasculitis, particularly the demyelinating brain
diseases.
Keywords
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Article info
Publication history
Published online: January 14, 2013
Accepted:
November 19,
2012
Received in revised form:
October 27,
2012
Received:
April 9,
2012
Identification
Copyright
© 2012 Elsevier B.V. Published by Elsevier Inc. All rights reserved.
